The study investigates the relationship of organizational factors such as perceived external prestige and perceived organizational support on well-being and turnover intention. Based on a sample of 484 medical sales representatives, the present study found support for the assertion that employees’ perception about the external prestige of their organization and support from the organization is positively related to well-being. The finding indicated a partial mediation effect of well-being on the relationship between both the organizational factors and turnover intention. The study argues that organizations need to focus their attention on employee well-being. The study adds to the existing literature by explaining the path in which the organizational factors influences employee turnover intention.